Approaches towards the synthesis of fluoro (cyclo) alkylamines

…, GWM Visser, W Menge, R Leurs, H Timmerman…

Index: Windhorst; Bechger; Visser; Menge; Leurs; Timmerman; Herscheid Journal of Fluorine Chemistry, 1996 , vol. 80, # 1 p. 35 - 40

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Citation Number: 5

Abstract

The synthesis of fluoro (cyclo) alkylamines 1-amino-6-fluorohexane (1), 1-amino-7- fluoroheptane (2), cis/trans-4-fluorocyclohexylamine (3a, b) and cis-4- fluoromethylcyclohexylamine (4) has been investigated for use as synthons for histamine receptor ligands for use in PET.