Simple and efficient method for the synthesis of azides in Water-THF solvent system

…, PV Ramana, SG Shirodkar

Index: Swetha; Ramana, P. Venkata; Shirodkar Organic Preparations and Procedures International, 2011 , vol. 43, # 4 p. 348 - 353

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Citation Number: 13

Abstract

The azide functionality is a common progenitor for the synthesis of N-containing compounds and not only reacts with nucleophiles and electrophiles but also serves as a nitrene precursor upon thermolysis or photolysis. 1, 2 Over the past decade, new perspectives have been developed for the use of azides in peptide chemistry, 3, 4 combinatorial chemistry5, 6 and heterocyclic synthesis. 7, 8 Current leading anti-HIV 1 drugs of purine and pyrimidine ...