Journal of the American Chemical Society

Metabolite Analogs. VI. Preparation of Some Analogs of 4-Amino-5-imidazole-carboxamide1

JRE Hoover, AR Day

Index: Hoover; Day Journal of the American Chemical Society, 1956 , vol. 78, p. 5832,5835

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Citation Number: 51

Abstract

1, 3, 3-Triazolc analogs of the itnidazole intermediates of de novo puriue synthesis have beer1 prepared its potential incdifierr of nucleic acid metabolism. The l-benzyl-1, 2, 3- triazoles mere formed readily by condensing benzyl azide with esters anti nitriles containing an active methylene group and the benzyl group WLS removed by reduction with sodium in liquid ammonia.