A new synthesis of phthalimidines

…, KY Suponitsky, LV Belousova, ZI Orlova

Index: Ukhin; Suponitsky; Belousova; Orlova Russian Chemical Bulletin, 2009 , vol. 58, # 12 p. 2478 - 2487 Izv. Akad. Nauk, Ser. Khim., 2009 , # 12 p. 2399 - 2407,9

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Citation Number: 4

Abstract

Abstract A new synthesis of phthalimidines is described. 3-Acyloxy-2-aryl-and 2-acylamino-3- acyloxyphthalimidines were prepared by the reaction of 3-arylaminophthalides or o- formylbenzoic acid acylhydrazones with acetic or propionic anhydrides. Their reactions with O-, N-, S-, and C-nucleophiles were studied. The structure of 2-acetyl (cyanoacetyl) amino-3- acetoxyindolin-1-one was confirmed by X-ray diffraction analysis.