Identification of a novel class of succinyl-nitrile-based Cathepsin S inhibitors

Y Bekkali, DS Thomson, R Betageri…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 9 p. 2465 - 2469

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Citation Number: 15

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... Department of Medicinal Chemistry, Boehringer Ingelheim ... 6 and 7 Due to its involvement in the antigen processing and presentation process, Cat S became an attractive target for medicinal chemists as inhibition may modulate ...