Asymmetric synthesis catalyzed by chiral ferrocenylphosphine transition metal complexes. 10 gold (i)-catalyzed asymmetric aldol reaction of isocyanoacetate
T Hayashi, M Sawamura, Y Ito
Index: Hayashi, Tamio; Sawamura, Masaya; Ito, Yoshihiko Tetrahedron, 1992 , vol. 48, # 11 p. 1999 - 2012
Full Text: HTML
Citation Number: 122
Abstract
Optically active ferrocenylbisphosphine ligands containing 2-(dialkylamino) ethylamino group on the ferrocenylmethyl position have been prepared and used for the gold (I)- catalyzed asymmetric aldol reaction of isocyanoacetate with aldehydes. Six-membered ring amines, such as morpholino or piperidino group, at the terminal of the side chain were most stereoselective to give optically active trans-4-methoxycarbonyl-5-alkyl-2-oxazolines (up ...
Related Articles:
Derivatives of 1: 3??bis??Phenylamino??Propane
[van Alphen Recueil des Travaux Chimiques des Pays-Bas, 1937 , vol. 56, p. 1007,1008]
Derivatives of 1: 3??bis??Phenylamino??Propane
[van Alphen Recueil des Travaux Chimiques des Pays-Bas, 1937 , vol. 56, p. 1007,1008]