A highly selective fluorescent probe for fast detection of hydrogen sulfide in aqueous solution and living cells.
Zheng Xu, Lin Xu, Ji Zhou, Yufang Xu, Weiping Zhu, Xuhong Qian
Index: Chem. Commun. (Camb.) 48(88) , 10871-3, (2012)
Full Text: HTML
Abstract
A new ratiometric fluorescence probe E1 based on an excited-state intramolecular proton transfer (ESIPT) mechanism for detection of hydrogen sulfide (H(2)S) is reported. E1 responds to H(2)S quickly and showed a 30-fold fluorescence enhancement in 2 minutes. Moreover, E1 can detect H(2)S quantitatively with a detection limit as low as 0.12 μM in aqueous solution. Its potential for biological applications was confirmed by employing it for fluorescence imaging of H(2)S in living cells.
Related Compounds
Related Articles:
Modulation of firefly luciferase stability and impact on studies of gene regulation.
1991-07-22
[Gene 103(2) , 171-7, (1991)]
2012-07-07
[Phys. Chem. Chem. Phys. 14(25) , 9016-25, (2012)]
2012-07-20
[J. Org. Chem. 77(14) , 6166-78, (2012)]
2012-10-09
[Chem. Commun. (Camb.) 48(78) , 9720-2, (2012)]
Active role of proton in excited state intramolecular proton transfer reaction.
2013-02-21
[J. Phys. Chem. A 117(7) , 1400-5, (2013)]