Synthesis of polyhydroxylated flavonoids bearing a lipophilic decyl tail as potential therapeutic antioxidants
ST Caldwell, DB McPhail, GG Duthie…
Index: Caldwell, Stuart T.; McPhail, Donald B.; Duthie, Garry G.; Hartley, Richard C. Canadian Journal of Chemistry, 2012 , vol. 90, # 1 p. 23 - 33
Full Text: HTML
Citation Number: 1
Abstract
Antioxidants have potential for the treatment of stroke and neurodegeneration, and chimeric compounds that combine a flavon-3-ol head group related to myricetin and a lipophilic decyl tail are known to protect membranes from oxidative damage at least as well as vitamin E. New flavon-3-ols that are highly hydroxylated in the B ring in ways not found in natural flavon-3-ols and bearing a lipophilic decyl tail have been prepared from trimethoxy-and ...
Related Articles:
[Chen, Fanglei; Zhang, Guiping; Hong, Zebin; Lin, Zhonghui; Lei, Min; Huang, Mingdong; Hu, Lihong Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 10 p. 2379 - 2382]
Oxidation of 1, 2, 4, 5-tetramethoxybenzene to a cation radical by cytochrome P450
[Sato, Hideaki; Guengerich, F. Peter Journal of the American Chemical Society, 2000 , vol. 122, # 33 p. 8099 - 8100]
[Stahl; Kissau; Mazitschek; Huwe; Furet; Giannis; Waldmann Journal of the American Chemical Society, 2001 , vol. 123, # 47 p. 11586 - 11593]
[Stahl; Kissau; Mazitschek; Huwe; Furet; Giannis; Waldmann Journal of the American Chemical Society, 2001 , vol. 123, # 47 p. 11586 - 11593]
[Stahl; Kissau; Mazitschek; Huwe; Furet; Giannis; Waldmann Journal of the American Chemical Society, 2001 , vol. 123, # 47 p. 11586 - 11593]