Synthesis of 3, 5??disubstituted 1??amino??1, 3, 5??triazine??2, 4, 6??triones (or 1??aminocyanurates) by cyclic transformation of 1, 3, 4??oxadiazol??2 (3H)??one derivatives

F Chau, JC Malanda, R Milcent

Index: Chau, Francois; Malanda, Jean-Claude; Milcent, Rene Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1603 - 1606

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Citation Number: 4

Abstract

Abstract The 5-aryl (or methyl)-3-phenylcarbamoyl-1, 3, 4-oxadiazol-2 (3H)-ones 2, in the presence of sodium hydride in anhydrous dimethylformamide, were transformed into 1- benzamido (or acetamido)-3, 5-diphenyl-1, 3, 5-triazine-2, 4, 6-trione derivatives 7 in poor yields. However, compounds 7 were obtained in better yields when the sodium salts of 5- aryl (or methyl)-1, 3, 4-oxadiazol-2 (3H)-ones 1 were treated with two equivalents of aryl ( ...