Regioselective synthesis of N-aminoisoindolones and mono-N-and di-N, N′-substituted phthalazones utilizing hydrazine nucleophiles in a palladium-catalyzed three …

…, C Kilner, D MacPherson, P Milner

Index: Fahmy, Amin F.; Sauer, Juergen; Youssef, Mohamed Salah K.; Halim, Mohamed Said Abdel; Hassan, Mamdouh A. Synthetic Communications, 1998 , vol. 28, # 15 p. 2871 - 2886

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Citation Number: 23

Abstract

... Volume: Page: ... In an effort to improve the efficiency of the reaction and to simplify the synthetic procedure, reaction conditions employing palladacycle 17 were then ... eluting with 3:7 v/v EtOAc−hexane) to give 15a (100 mg, 60%) as a pale brown gum: R f 0.25 (3 ...