Chemoselective Esterification and Amidation of Carboxylic Acids with Imidazole Carbamates and Ureas
ST Heller, R Sarpong
Index: Heller, Stephen T.; Sarpong, Richmond Organic Letters, 2010 , vol. 12, # 20 p. 4572 - 4575
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Citation Number: 40
Abstract
The chemoselective esterification of carboxylic acids is a ubiquitous synthetic operation. In addition to the venerable Fischer esterification,(1) numerous other methods have been developed toward this end. Transformations that involve activation of the carboxylic acid group have become a mainstay of ester synthesis, and though substantial progress has been made in this area,(2) acid activation often adds an additional step and can be challenging in the presence of ...
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