Organic letters

Synthesis of new, pyrene-containing, metal-chelating lipids and sensing of cupric ions

BC Roy, B Chandra, D Hromas, S Mallik

Index: Roy, Bidhan C.; Chandra, Binita; Hromas, Daniel; Mallik, Sanku Organic Letters, 2003 , vol. 5, # 1 p. 11 - 14

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Citation Number: 69

Abstract

The syntheses of several saturated, pyrene-containing, metal-chelating lipids are described. These lipids are capable of strongly binding to transition metal ions employing the metal- chelating headgroup. The excimer-to-monomer ratio of the pyrene groups changes with addition of cupric ions to the liposomes. Three other transition metal ions (Zn2+, Ni2+, and Hg2+) did not cause any appreciable changes in the excimer-to-monomer ratio.

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