Inhibin alpha-subunit, Melan A and MNF116 in pheochromocytomas.

Diana Păun, Marius Cristian Neamţu, Elena Taina Avramescu, Mădălina Gabriela Georgescu, Rodica Petriş, Dana Terzea, Cătălina Poiană, Sorin Păun

Index: Rom. J. Morphol. Embryol. 55(3) , 905-8, (2014)

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Abstract

The aim of this study was to make immunohistochemical analyses with Inhibin alpha-subunit, Melan A and MNF116 (pan-Cytokeratin antibody) in pheochromocytomas, because immunohistochemistry is useful for the distinction between adrenal tumors.We used 20 patients with pheochromocytomas submitted to laparoscopic (n=19) or classical (n=1) surgery and we have explored immuno-staining with Inhibin alpha-subunit, Melan A and MNF116 in these tumors. This can be helpful when we cannot make the distinction between adrenal tumors.Pheochromocytomas did not stain with Inhibin alpha-subunit, Melan A and MNF116.In our study, Inhibin alpha-subunit, Melan A and MNF116 were not sensitive for pheochromocytomas.