The synthesis of the high-potency sweetener, NC-00637. Part 2: Preparation of the pyridine moiety

DJ Ager, RA Erickson, DE Froen…

Index: Organic Process Research and Development, , vol. 8, # 1 p. 62 - 71

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Citation Number: 9

Abstract

... a toll manufacturer for scale-up with a slight variation with regard to the workup procedure. ... with isopropyl acetate so that higher temperatures could be employed during the separation process than when ... In this way, the product remained in the organic phase and did not have to ...