Stereoselective synthesis of 1-substituted 2, 6-dicyanopiperidines and transformation of 2, 6-dialkylated products of 1-phenyl-2, 6-dicyanopiperidine to. delta.- …

K Takahashi, T Mikajiri, H Kurita…

Index: Takahashi, Kazumasa; Mikajiri, Tsutomu; Kurita, Hideki; Ogura, Katsuyuki; Iida, Hirotada Journal of Organic Chemistry, 1985 , vol. 50, # 22 p. 4372 - 4375

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Citation Number: 19

Abstract

Received November I, 1984 a-Amino nitriles are the masked acyl anion equivalents and useful reagents for preparation of ket0nes. l Several synthetic methods have been reported for the preparation of 1-alkyl-and l-amin0-2, 6-dicyanopiperidines,~ being cyclic a-amino nitriles. There is, however, no information about their utility as the masked diacyl dianions equivalents of glutaraldehyde. Furthermore, their stereochemistryZa has not been ...

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