The discovery of tetrahydro-β-carbolines as inhibitors of the kinesin Eg5
PA Barsanti, W Wang, ZJ Ni, D Duhl…
Index: Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 1 p. 157 - 160
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Citation Number: 54
Abstract
... Bioorganic & Medicinal Chemistry Letters. ... Molecular modeling and medicinal chemistry techniques were employed to explore the SAR for this series with a focus of removing potential metabolic liabilities and improving cellular potency. ...
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