Organometallics

A practical synthesis of (dichloromethyl)-and (1, 1-dichloroethyl) boronic esters

DS Matteson, GD Hurst

Index: Matteson, Donald S.; Hurst, Gerald D. Organometallics, 1986 , vol. 5, p. 1465 - 1467

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Citation Number: 21

Abstract

Addition of lithium diisopropylamide or diethylamide to a mixture of triisopropyl borate and dichloromethane in THF at temperatures between-78 and 0" C leads to formation of (dichloromethy1) lithium and its capture by the borate ester. Anhydrous HC1 converts the resulting borate salt to diisopropyl (dichloromethy1) boronate. Similarly, dimethyl (1, l- dichloroethy1) boronate is readily prepared from 1, ldichloroethane and trimethyl borate. ...