Improved synthesis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives catalyzed by urea under ultrasound.

Ji-Tai Li, Yan-Wei Li, Ya-Li Song, Guo-Feng Chen, Ji-Tai Li, Yan-Wei Li, Ya-Li Song, Guo-Feng Chen, Ji-Tai Li, Yan-Wei Li, Ya-Li Song, Guo-Feng Chen

Index: Ultrason. Sonochem. 19(1) , 1-4, (2012)

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Abstract

Synthesis of 2,2'-arylmethylene bis(3-hydroxy-5,5-dimethyl-2-cyclohexene-1-one) derivatives catalyzed by urea via the condensation of aromatic aldehydes and 5,5-dimethyl-1,3-cyclohexanedione was carried out in 80-98% yields at 50 °C in aqueous media under ultrasound. This method provides several advantages such as environment friendliness, high yields and simple work-up procedure.Copyright © 2011 Elsevier B.V. All rights reserved.