Uncatalysed coupling of an activated aryl chloride with aryllithium and aryl Grignard reagents
D Astley, H Saygı, S Gezer, ST Astley
Index: Astley, Demet; Saygi, Hava; Gezer, Sibel; Astley, Stephen T. Tetrahedron Letters, 2004 , vol. 45, # 39 p. 7315 - 7317
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Citation Number: 7
Abstract
Substitution of the chloro group in 2-(2-chlorophenyl)-4, 4-dimethyl-2-oxazoline to afford biaryls occurs upon reaction with either aryllithium reagents or aryl Grignard reagents. The reactions with Grignard reagents occur under similar conditions to a previously reported manganese-catalysed procedure. The reactions with lithium reagents, whilst not always affording greater yields of product than the Grignard reagents, involve much shorter ...
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