A Palladium Catalyzed, Multicomponent Approach to beta-Lactams via Aryl Halide Carbonylation

GM Torres, M De La Higuera, JS Quesnel…

Index: Evans, Caroline D.; Mahon, Mary F.; Andrews, Philip C.; Muir, James; Bull, Steven D. Organic Letters, 2011 , vol. 13, # 23 p. 6276 - 6279

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Abstract

... structural core in a diverse range of products, including natural products (eg, β-lactam-based antibiotics),(1) related biologically active compounds,(2) monomers for polyamide synthesis,(3) and as synthetic precursors in organic chemistry.(4 ... Table d ... 1% Pd(P t Bu 3 ) 2 , 70 ° ...