Thiourea inhibitors of herpes viruses. Part 2: N-Benzyl-N′-arylthiourea inhibitors of CMV

…, KJ Curran, F Donahue, EB Norton, E Terefenko…

Index: Bloom, Jonathan D.; Dushin, Russell G.; Curran, Kevin J.; Donahue, Fran; Norton, Emily B.; Terefenko, Eugene; Jones, Thomas R.; Ross, Adma A.; Feld, Boris; Lang, Stanley A.; DiGrandi, Martin J. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3401 - 3406

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Citation Number: 33

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of highly potent thiourea inhibitors of cytomegalovirus (CMV) with improved stability properties was prepared and evaluated. Compound 29 inhibited the virus in cultured HFF cells with IC 50 of 0.2 nM. ... A series of highly potent thiourea inhibitors of cytomegalovirus (CMV) with ...