The Journal of Organic Chemistry

Nucleophilic Substitution in Fluoroalkyl Sulfates, Sulfonates, and Related Compounds

WV COHEN

Index: Cohen,W.V. Journal of Organic Chemistry, 1961 , vol. 26, p. 4021 - 4026

Full Text: HTML

Citation Number: 11

Abstract

New chemistry based on highly fluorinated alcohols is described. The difficult nucleophilic substitution at the carbonoxygen bond of polyfluoroalkoxy compounds takes place at appreciably lower temperatures in the chlorosulfate and sulfate esters than in the tosyl esters. Fluoroalkylamines have been prepared from the corresponding alcohols going through one intermediate step.