Annales Pharmaceutiques Françaises 1996-01-01

[Synthesis and structural study of 5-arylidene thiazolidine-2,4-diones and 3-substituted-4-thio-imidazolidine-2-ones].

JF Albuquerque, LC Azevedo, SL Galdino, J Chantegrel, IR Pitta, C Luu-Duc

Index: Ann. Pharm. Fr. 53(5) , 209-14, (1995)

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Abstract

The synthesis and the physico-chemical properties of four 3-(4-bromophenacyl)-5-arylidene-thiazolidine-2,4-diones, two 3-(4-bromobenzyl)-5-arylidene-thiazolidine-2,4-diones and seven 3-(4-chlorobenzyl)-5-arylidene-4-thio-imidazolidine-2-ones were described. These products were synthetized by the aldolisation-crotonisation reaction between aromatic aldehydes and substituted thiazolidinediones or thio-imidazolidinones.

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