An efficient chemomicrobiological synthesis of stable isotope-labeled L-tyrosine and L-phenylalanine

TE Walker, C Matheny, CB Storm…

Index: Walker, T. E.; Matheny, C.; Storm, C. B.; Hayden, H. Journal of Organic Chemistry, 1986 , vol. 51, # 8 p. 1175 - 1179

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Citation Number: 33

Abstract

7 a. 3'. 5*-'3c2 b. 4'-'3C proceeded smoothly. 10 Filtration into HC1 gave the protonated anilinium species, which is stable to air oxidation. An equivalent amount of NaNOz was added to the cold solution, and after 1 h an excess of hypophosphorous acid was added. The formation of phenol, as followed by 13C NMR, was complete after 4-5 days at room temperature. The phenol was isolated by ether extraction followed by codistillation with ...