Screening and confirmation of thyreostatics in urine by gas chromatography with nitrogen-phosphorus detection and gas chromatography-mass spectrometry after sample clean-up with a mercurated affinity column.
R Schilt, J M Weseman, H Hooijerink, H J Korbee, W A Traag, M J van Steenbergen, W Haasnoot
Index: J. Chromatogr. A. 489(1) , 127-37, (1989)
Full Text: HTML
Abstract
Methods are described for the screening and confirmation of residues of the thyreostatics thiouracil, methylthiouracil and propylthiouracil in urine samples of cattle at levels down to 25 micrograms/l. After a selective preconcentration of the thiol-containing thyreostatics on a mercurated affinity column, the analytes are derivatized by extractive alkylation and analysed by gas chromatography with nitrogen-phosphorus or mass spectrometric detection.
Related Compounds
Related Articles:
2015-06-01
[Anal. Bioanal. Chem 407 , 4423-35, (2015)]
2005-05-13
[J. Chromatogr. A. 1074 , 1-7, (2005)]
Capillary zone electrophoresis determination of thyreostatic drugs in urine.
1998-01-01
[J. Capillary Electrophor. 5 , 9-12, (1998)]
Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.
1992-04-01
[Antiviral Res. 17(4) , 245-64, (1992)]
2000-12-01
[J. Mol. Cell. Cardiol. 32(12) , 2221-8, (2000)]