Synthesis of 3-fluoroazetidines.
Willem Van Brabandt, Guido Verniest, Dirk De Smaele, Guillaume Duvey, Norbert De Kimpe
Index: J. Org. Chem. 71 , 7100, (2006)
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Abstract
N-(Alkylidene or 1-arylmethylidene)-2-propenylamines were regiospecifically functionalized to novel N-(alkylidene or 1-arylmethylidene)-3-bromo-2-fluoropropylamines, which were proven to be excellent precursors for 3-fluoroazetidines.
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