Cardenolide and oxypregnane glycosides from the root of Asclepias incarnata L.
T Warashina, T Noro
Index: Chem. Pharm. Bull. 48(4) , 516-24, (2000)
Full Text: HTML
Abstract
Twenty-nine new oxypregnane glycosides were obtained along with two known cardenolides, frugoside and gofruside, and three known 12-O-acylated pregnane glycosides from the roots of Asclepias incarnata L. (Asclepiadaceae). By detailed studies of the 1H- and 13C-NMR spectra, the structures were determined to be tri- to penta glycosides of isolineolon, 12-O-acetyllineolon, ikemagenin, 12-O-benzoylisolineolon, and two new 12-O-acylated pregnanes.
Related Compounds
Related Articles:
Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs.
2011-04-01
[Bioorg. Med. Chem. 19 , 2407-17, (2011)]
C3'/C4'-Stereochemical Effects of Digitoxigenin α-L-/α-D-Glycoside in Cancer Cytotoxicity.
2013-01-01
[ChemMedChem 8 , 63, (2013)]
Assembly of digitoxin by gold(I)-catalyzed glycosidation of glycosyl o-alkynylbenzoates.
2011-12-02
[J. Org. Chem. 76 , 9748, (2011)]
Integrating high-content screening and ligand-target prediction to identify mechanism of action.
2008-01-01
[Nat. Chem. Biol. 4 , 59-68, (2008)]
2010-04-01
[Planta Med. 76(6) , 561-5, (2010)]