Aromatic sulfonyl fluorides covalently kinetically stabilize transthyretin to prevent amyloidogenesis while affording a fluorescent conjugate
NP Grimster, S Connelly, A Baranczak…
Index: Journal of the American Chemical Society, , vol. 135, # 15 p. 5656 - 5668
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Citation Number: 29
Abstract
... Journal of the ... 2013, 135 (15), pp 5656–5668. DOI: 10.1021/ja311729d. Publication Date (Web): January 25, 2013. Copyright © 2013 American Chemical Society. ... of TTR over its dissociative transition state, and their collective structure–activity relationships allowed us to conceive ...
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[Grimster, Neil P.; Connelly, Stephen; Baranczak, Aleksandra; Dong, Jiajia; Krasnova, Larissa B.; Sharpless, K. Barry; Powers, Evan T.; Wilson, Ian A.; Kelly, Jeffery W. Journal of the American Chemical Society, 2013 , vol. 135, # 15 p. 5656 - 5668]