Binding of eugenol and o-ethoxybenzoic acid to bovine serum albumin.

S Fujisawa, E Masuhara

Index: J. Dent. Res. 60(4) , 860-4, (1981)

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Abstract

The binding constants (log K) of eugenol, o-ethoxy-benzoic acid, and their analogues, plus other organic compounds widely used in dentistry with bovine serum albumin, were examined with respect to the partition coefficients of these compounds in octanol-water (log P). Linear relationships between log K and log P values were obtained with high relative coefficients. Eugenol and o-ethoxybenzoic acid showed a relatively large log K value.