Organic & Biomolecular Chemistry 2009-08-21

A concise total synthesis of (+/-)-acutifolone A.

Ming-Tsang Hsieh, Hsing-Jang Liu, Tai Wei Ly, Kak-Shan Shia

Index: Org. Biomol. Chem. 7(16) , 3285-90, (2009)

Full Text: HTML

Abstract

Starting from 4-methylcyclohexanone (7), a concise total synthesis of the pinguisane-type sesquiterpenoid acutifolone A, in racemic form, has been accomplished in 14 steps with an overall yield of 14.5%.