Organic & Biomolecular Chemistry 2011-03-07

A novel α-isocyanoacetamide-based three-component reaction for the synthesis of dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates.

Riccardo Mossetti, Diego Caprioglio, Giampiero Colombano, Gian Cesare Tron, Tracey Pirali

Index: Org. Biomol. Chem. 9(5) , 1627-31, (2011)

Full Text: HTML

Abstract

α-Isocyanoacetamides, acyl chlorides and dialkylacetylenedicarboxylates undergo a smooth multicomponent reaction to produce dialkyl 2-acyl-5-aminofuran-3,4-dicarboxylates in good yield. The scope and mechanism of this new multicomponent transformation are discussed.

Related Compounds

Related Articles:

Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.

2011-02-01

[Mol. Divers. 15(1) , 263-7, (2011)]

Controlled synthesis of Fe3O4/ZIF-8 nanoparticles for magnetically separable nanocatalysts.

2015-04-27

[Chemistry 21(18) , 6879-87, (2015)]

Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.

2011-01-01

[Molecules 16(5) , 3723-39, (2011)]

Kinetic and mechanistic analyses of new classes of inhibitors of two-component signal transduction systems using a coupled assay containing HpkA-DrrA from Thermotoga maritima.

2004-04-01

[Microbiology 150(Pt 4) , 885-96, (2004)]

An ultraviolet-spectrophotometric method with 2-cyanoacetamide for the determination of the enzymatic degradation of reducing polysaccharides.

1992-06-01

[Anal. Biochem. 203 , 335-339, (1992)]

More Articles...