New reactivity of nitropyrimidinone: Ring transformation and NC transfer reactions
N Nishiwaki, K Matsushima, M Chatani, M Tamura…
Index: Nishiwaki, Nagatoshi; Matsushima, Kazuo; Chatani, Miki; Tamura, Mina; Ariga, Masahiro Synlett, 2004 , # 4 p. 703 - 707
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Citation Number: 11
Abstract
Abstract Nitropyrimidinone 1 revealed new reactivity upon treatment with active methylene compounds 2 under basic conditions. The N1-C2-C3-C4 moiety of 1 combined with two carbon units of 2 affording polyfunctionalized pyridones 4, which was hitherto unknown ring transformation. On the other hand, the N1-C2 moiety of 1 was transferred to the methylene group of 2 giving functionalized enamines 3. It was also possible to modify the amino ...
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