Journal of Bone & Joint Surgery, British Volume 1985-03-01

The use of Dexon as a replacement for the calcaneal tendon in sheep.

C B Howard, B McKibbin, Z A Rális

Index: J. Bone Joint Surg. Br. 67(2) , 313-6, (1985)

Full Text: HTML

Abstract

We have studied the use of filamentous polyglycolic acid (Dexon) for the induction of neotendon in the calcaneal tendon of sheep. Uniformly good results were obtained, with the formation of a thick neotendon. However, in a control group the power of spontaneous regeneration of the tendon was studied; it was found that, provided overlengthening of the gap was prevented, an equally good tendon resulted. It is concluded that this particular model is not an appropriate one for testing neotendon induction, despite its use for this purpose in the past. The favourable results of using filamentous polyglycolic acid as a tendon replacement suggest that it should be further investigated (in a more suitable model) since it may well have useful clinical applications.


Related Compounds

Related Articles:

CYP2C9 genotype vs. metabolic phenotype for individual drug dosing--a correlation analysis using flurbiprofen as probe drug.

2015-01-01

[PLoS ONE 10(3) , e0120403, (2015)]

Experimental evaluation of a new composite mesh with the selective property of incorporation to the abdominal wall without adhering to the intestines.

1994-03-01

[J. Biomed. Mater. Res. 28(3) , 373-5, (1994)]

Safety evaluation of a triazine compound nitromezuril by assessing bacterial reverse mutation, sperm abnormalities, micronucleus and chromosomal aberration.

2015-04-01

[Regul Toxicol Pharmacol 71(3) , 585-9, (2015)]

Intestinal complications associated with use of the Dexon mesh sling in gynecologic oncology patients.

1990-07-01

[Gynecol. Oncol. 38(1) , 146-8, (1990)]

Absorbable mesh in the treatment of rectal prolapse.

1988-08-01

[Int. J. Colorectal Dis. 3(3) , 141-3, (1988)]

More Articles...