Tetrahedron letters

Synthesis of chiral nonracemic polyimine macrocycles from cyclocondensation reactions of biaryl and terphenyl aromatic dicarboxaldehydes and 1R, 2R- …

N Kuhnert, C Patel, F Jami

Index: Kuhnert, Nikolai; Patel, Chirag; Jami, Fatemeh Tetrahedron Letters, 2005 , vol. 46, # 44 p. 7575 - 7579

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Citation Number: 31

Abstract

The synthesis of biaryl and terphenyl dicarboxaldehydes using Suzuki coupling methodology and their macrocyclisation reactions with 1R, 2R-diaminocyclohexane yielding novel polyimine macrocycles derived from the [2+ 2] and [3+ 3] cyclocondensation reactions is presented. The ratio of products was found to depend on the overall geometry of the dicarboxaldehydes.

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