Structure–activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode
RC Neugebauer, U Uchiechowska…
Index: Fries; Schimmelschmidt Justus Liebigs Annalen der Chemie, 1930 , vol. 484, p. 245,271
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Citation Number: 132
Abstract
... Volume: Page: ... Thus, we initially prepared a series of β-aryl-8-bromosplitomicins 5a−p and 5r by the acid-catalyzed cyclization of cinnamic acids 7a and 7c−e with β-naphthols 6a−h (see Scheme 1 and Table 1). Similarly, the use of acrylic acid (7b) instead of a ...
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