Direct generation of triketide stereopolyads via merged redox-construction events: total synthesis of (+)-zincophorin methyl ester

…, X Gao, RM Lipinski, MJ Krische

Index: Del Valle, David J.; Krische, Michael J. Journal of the American Chemical Society, 2013 , vol. 135, # 30 p. 10986 - 10989

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Citation Number: 12

Abstract

(+)-Zincophorin methyl ester is prepared in 13 steps (longest linear sequence). A bidirectional redox-triggered double anti-crotylation of 2-methyl-1, 3-propane diol directly assembles the triketide stereopolyad spanning C4–C12, significantly enhancing step

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