Lactone formation in the oxidation of diols with N-iodosuccinimide and silver acetate

…, R Adkins, R Baldridge, V Hensley…

Index: Beebe, Thomas R.; Adkins, Rick; Baldridge, Ruth; Hensley, Vivian; McMillen, Doug; et al. Journal of Organic Chemistry, 1987 , vol. 52, # 24 p. 5472 - 5474

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Citation Number: 8

Abstract

Recently,'we found that primary and secondary alcohols were oxidized to aldehydes and ketones when treated in the dark with N-iodosuccinimide (NIS), silver acetate, and heat. Tertiary alcohols were unaffected when subjected to these same reaction conditions. In this new study we have oxidized four symmetrical diprimary diols (1, 4-butanediol, 1, 5- pentanediol, 1, 6-hexanediol, and 1, 2-benzenedimethanol) and one unsymmetrical ...