Aminomethylation of Thiophene. III. 1, 2 Improved Synthesis of the 2-Thenylamines

HD Hartough, SL Meisel

Index: Hartough; Meisel Journal of the American Chemical Society, 1948 , vol. 70, p. 4018

Full Text: HTML

Citation Number: 8

Abstract

The reactivity of the methylene radical in N-(2-theny1)-formaldimine has been demonstrated previously. 2 It: has also been shown that in the aminomethylation of thiophene the 2- thenylamine (I) is formed as a secondary product by the reaction of N-(2-theny1)- formaldimine (11) with thiophene and not as a primary product as originally believed. Di-(2- thenyl)-amine (111) was also shown to form in this reaction when acetic acid was present ...

Related Articles:

Highly chemoselective reductive amination-coupling by one-pot reaction of aldehydes, HMDS and NaBH 4

[Azizi, Najmedin; Akbari, Elham; Amiri, Alireza Khejeh; Saidi, Mohammad R. Tetrahedron Letters, 2008 , vol. 49, # 47 p. 6682 - 6684]

Highly chemoselective reductive amination-coupling by one-pot reaction of aldehydes, HMDS and NaBH 4

[Azizi, Najmedin; Akbari, Elham; Amiri, Alireza Khejeh; Saidi, Mohammad R. Tetrahedron Letters, 2008 , vol. 49, # 47 p. 6682 - 6684]

Unexpected selectivity in ruthenium-catalyzed hydrosilylation of primary amides: synthesis of secondary amines

[Li, Bin; Sortais, Jean-Baptiste; Darcel, Christophe Chemical Communications, 2013 , vol. 49, # 35 p. 3691 - 3693]

Homogeneous hydrogenations of nitriles catalyzed by rhenium complexes

[Rajesh, Kunjanpillai; Dudle, Balz; Blacque, Olivier; Berke, Heinz Advanced Synthesis and Catalysis, 2011 , vol. 353, # 9 p. 1479 - 1484]

Antispasmodics. XII. Secondary and Tertiary Amines which Contain an ι-(2-Thienyl)-alkyl Group

[Blicke; Leonard Journal of the American Chemical Society, 1952 , vol. 74, p. 5105]

More Articles...