Biosynthetic-studies on tajixanthone and shamixanthone, polyketide hemiterpenoid metabolites of Aspergillus variecolor

…, E Bardshiri, CR McIntyre, TJ Simpson

Index: Ahmed, Salman A.; Bardshiri, Esfandiar; McIntyre, C. Rupert; Simpson, Thomas J. Australian Journal of Chemistry, 1992 , vol. 45, # 1 p. 249 - 274

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Citation Number: 29

Abstract

Abstract The biosynthesis of tajixanthone and related metabolites of Aspergillus variecolor has been studied by incorporation experiments with simple and advanced precursors labelled with the stable isotopes 13 C, 2 H and 18 O. Tajixanthone is shown to be derived through ring cleavage of an octaketide-derived anthraquinone with introduction of two dimethylallyl moieties. From the results of isotopic labelling experiments and chemical ...