Novel 6-azapteridines from bifunctional 1, 2, 4-triazines

H Wamhoff, M Tzanova

Index: Wamhoff, Heinrich; Tzanova, Milena Collection of Czechoslovak Chemical Communications, 2003 , vol. 68, # 5 p. 965 - 974

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Citation Number: 3

Abstract

Abstract The convergent synthesis of ethyl 5-chloro-and 5-amino-3-aryl-1, 2, 4- triazinecarboxylates 9a-9d and 10a-10d as well as of 5-amino-3-aryl-1, 2, 4-triazine-6- carboxamides 11a-11d is described. Compounds 9, 10 and 11 are powerful key compounds for cyclization reactions to the novel pyrimido [4, 5-e][1, 2, 4] triazines 13d, 14c, 14d, 15c and 17a, 17d.