Synthesis and antiulcer activity of 5, 11-dihydro [1] benzoxepino [3, 4-b] pyridines

T Kumazawa, H Harakawa, H Obase…

Index: Kumazawa, Toshiaki; Harakawa, Hiroyuki; Obase, Hiroyuki; Oiji, Yoshimasa; Tanaka, Hiroshi; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 4 p. 779 - 785

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Citation Number: 18

Abstract

The general synthetic method for the compounds V listed in Table I1 was as found in Scheme 11. Method A. The alcohol 7 was chlorinated by SOCl? in CHzClz to give the chloride, which was treated with amine in CHzClz to give the diamines VA (compounds 10- 21 and

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