Journal of Clinical Microbiology 2009-12-01

Practical disk diffusion test for detecting group B streptococcus with reduced penicillin susceptibility.

Kouji Kimura, Jun-Ichi Wachino, Hiroshi Kurokawa, Satowa Suzuki, Kunikazu Yamane, Naohiro Shibata, Yoshichika Arakawa

Index: J. Clin. Microbiol. 47(12) , 4154-7, (2009)

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Abstract

Although group B streptococcus (GBS) has been considered to be uniformly susceptible to beta-lactams, the presence of GBS with reduced penicillin susceptibility (PRGBS) was recently confirmed genetically. We developed a feasible and reliable method for screening PRGBS in clinical microbiology laboratories using a combination of ceftibuten, oxacillin, and ceftizoxime disks.