Tetrahedron Letters

Cyanuric chloride: an efficient reagent for the Lossen rearrangement

F Hamon, G Prié, F Lecornué, S Papot

Index: Hamon, Florian; Prie, Gildas; Lecornue, Frederic; Papot, Sebastien Tetrahedron Letters, 2009 , vol. 50, # 49 p. 6800 - 6802

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Citation Number: 32

Abstract

An efficient method for the Lossen rearrangement that uses 2, 4, 6-trichloro-1, 3, 5-triazine (TCT) as a promoter is reported. This procedure allowed the preparation of various carbamates, thiocarbamates, and ureas in good yields directly from the corresponding hydroxamic acids.

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