Tetrahedron Letters

In situ-generated N-thiocyanatosuccinimide (NTS) as a highly efficient reagent for the one-pot thiocyanation or isothiocyanation of alcohols

B Mokhtari, R Azadi, S Rahmani-Nezhad

Index: Mokhtari, Babak; Azadi, Roya; Rahmani-Nezhad, Samira Tetrahedron Letters, 2009 , vol. 50, # 47 p. 6588 - 6589

Full Text: HTML

Citation Number: 14

Abstract

The first application of in situ-generated N-thiocyanatosuccinimide (NTS) for the thiocyanation of alcohols is described. This method can be easily applied for the facile conversion of primary, secondary and tertiary alcohols into the corresponding alkyl thiocyanates or alkyl isothiocyanates in good to excellent yields.

Related Articles:

Efficient Conversion of Tetrahydropyranyl (THP) Ethers to Their Corresponding Thiocyanates With in-situ–Generated Ph3P (SCN) 2

[Iranpoor, Nasser; Firouzabadi, Habib; Shaterian, Hamid Reza Phosphorus, Sulfur and Silicon and the Related Elements, 2005 , vol. 180, # 9 p. 2093 - 2096]

Transformation of Primary Amines to Thiols, Sulfides, or Arylmethyl Thiocyanates via Pyridinium Salts

[Molina, P.; Alajarin, M.; Ferao, A.; Lidon, M. J.; Fresneda, P. M.; Vilaplana, M. J. Synthesis, 1982 , # 6 p. 472 - 475]

Transformation of Primary Amines to Thiols, Sulfides, or Arylmethyl Thiocyanates via Pyridinium Salts

[Molina, P.; Alajarin, M.; Ferao, A.; Lidon, M. J.; Fresneda, P. M.; Vilaplana, M. J. Synthesis, 1982 , # 6 p. 472 - 475]

Total synthesis of azinomycin A

[Yadav, Lal Dhar S.; Garima; Kapoor, Ritu Synthetic Communications, 2011 , vol. 41, # 1 p. 100 - 112]

More Articles...