Tetrahedron Letters

Synthesis of substituted 1, 2-dihydroquinolines and quinolines using ene–ene metathesis and ene–enol ether metathesis

…, C Theeraladanon, A Nishida, M Nakagawa

Index: Arisawa, Mitsuhiro; Theeraladanon, Chumpol; Nishida, Atsushi; Nakagawa, Masako Tetrahedron Letters, 2001 , vol. 42, # 45 p. 8029 - 8033

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Citation Number: 109

Abstract

We describe a novel and convenient method for quinoline synthesis using ring-closing olefin metathesis (RCM), ene–ene metathesis, and ene–enol ether metathesis. We also report the first example of enol silyl ether–ene metathesis to produce cyclic enol silyl ether. Using this method, versatile substituted quinoline derivatives were readily prepared in excellent yield from anthranilic acid derivatives.