The Journal of Organic Chemistry

Aryl mesylates in metal catalyzed homocoupling and cross-coupling reactions. 2. Suzuki-type nickel-catalyzed cross-coupling of aryl arenesulfonates and aryl …

V Percec, JY Bae, DH Hill

Index: Percec, Virgil; Bae, Jin-Young; Hill, Dale H. Journal of Organic Chemistry, 1995 , vol. 60, # 4 p. 1060 - 1065

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Citation Number: 250

Abstract

The Ni (0)-catalyzed Suzuki-type cross-coupling reaction of various aryl sulfonates including mesylate with arylboronic acids in the presence of &PO4 is reported. The Ni (0) catalyst is generated in situ from NiCl2 (dppf) and Zn. This novel reaction, which yields unsymmetrical biaryls in good yields under mild conditions, is highly regiospecific and tolerates various functional groups. The influence of the effects of the substituent of the aromatic substrates, ...

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