A new synthesis of indoles
JA Murphy, KA Scott, RS Sinclair, N Lewis
Index: Murphy, John A.; Scott, Karen A.; Sinclair, Rhona S.; Lewis, Norman Tetrahedron Letters, 1997 , vol. 38, # 41 p. 7295 - 7298
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Citation Number: 47
Abstract
Indoles display a wide range of biological activities; this is exemplified by the amino-acid tryptophan (1), the hormones serotonin (2) and melatonin (3), the anti-arthritic indomethacin (4), the psychotropic LSD (5) and the anti-tumour agent vinblastine (6). Accordingly, the synthesis of indoles has long been a topic of fundamental interest to organic and medicinal chemists, and many of the 'named' syntheses of indoles are long established and associated with famous chemists ...
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