Synthetic Communications

Mild and Efficient Syntheses of 1-Aryl-3, 4-dihydroisoquinolines and 1-Aryl-3, 4-dihydro-β-carbolines via Regiospecific β-Eliminations of the Corresponding N-Tosyl-1, …

J Dong, XX Shi, J Xing, JJ Yan

Index: Dong, Jing; Shi, Xiao-Xin; Xing, Jing; Yan, Jing-Jing Synthetic Communications, 2012 , vol. 42, # 19 p. 2806 - 2817

Full Text: HTML

Citation Number: 6

Abstract

1-Substituted 3,4-DHIQs and 3,4-DHBCs normally can be obtained via Bischler–Napieralski cyclization of N-2-aryl/indolyl ethyl amides [ 7 7. (a) Bischler , A. ; Napieralski , B. A new method for the synthesis of isoquinolines . Ber. 1893 , 26 , 1903 – 1908 ; (b) Whaley , WM ; Govindachari , TR Preparation of 3,4-dihydroisoquinolines and related compounds by Bischler–Napieralski reaction . Org. React. 1951 , 6 , 74 – 150 ; (c) Fodor , G. ; Nagubandi , S. Correlation of the ...