4-Thio and 2, 4-Dithio 5, 5-Dialkylthiobarbituric Acids
JH Boothe, CO Wilson
Index: Boothe; Wilson Journal of the American Chemical Society, 1946 , vol. 68, p. 449
Full Text: HTML
Citation Number: 4
Abstract
Early in the history of barbituric acid synthesis, a fe. w 2-thiobarbiturates were prepared for the purpose of converting them into the corresponding oxygen analogs. In fact, Fischer and Dilthey2 reported the preparation of 5, s-diethyl-% thiobarbituric acid in their original paper in 1904. Until 1935, however, no systematic attempt was made to prepare a series of these compounds and evaluate them pharmacologically. This was probably due to the fact that ...
Related Articles:
[Varie, David L.; Shih, Chuan; Hay, David A; Andis, Sherri L.; Corbett, Tom H.; Gossett, Lynn S.; Janisse, Samantha K.; Martinelli, Michael J.; Moher, Eric D.; Schultz, Richard M.; Toth, John E. Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 369 - 374]
[Ghaib, Amar; Menager, Sabine; Verite, Philippe; Lafont, Olivier Farmaco, 2002 , vol. 57, # 2 p. 109 - 116]