Tetrahedron letters

An easy route to synthesize 1, 5-arylodiazepin-2-ones

K Bougrin, AK Bennani, SF Tétouani, M Soufiaoui

Index: Bougrin, Khalid; Bennani, A. Kella; Tetouani, Souad Fkih; Soufiaoui, Mohamed Tetrahedron Letters, 1994 , vol. 35, # 45 p. 8373 - 8376

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Citation Number: 57

Abstract

Abstract A series of 1, 5-arylodiazepin-2-ones is prepared by the condensation of the appropriate o-β-arylenediamines with β-ketoesters in xylene under microwave irradiation. The reaction time is shortened to 10 mn, and the products are obtained in high yields. No by products are observed. Specific effects of microwaves are evidenced as no reaction occurs by classical heating in the same conditions.